School of Medicine, Creighton University, Omaha NE
"Detection of residual prions from decontaminated medical and laboratory surfaces"
Department of Pathology, Case Western Reserve University
"Investigating prion protein seeding activity in Alzheimer’s disease and chronic traumatic encephalopathy"
MRC Prion Unit at UCL, Institute of Prion Diseases, London
"Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention"
MRC Prion at UCL, Institute of Prion Diseases, London
"Elucidating the factors required for propagating human CJD prions"
Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Victoria, Australia
"Risk of cancer from reduced expression of PrPC-implications for prion disease treatment"
Department of Physiology and Biophysics, School of Medicine; Case Western Reserve University, Cleveland, OH
"High-resolution structure determination of MM1 and MM2 sCJD prions"
Instructor, Department of Biochemistry, Boston University School of Medicine
"The identification of PrPSc interaction partners and the characterization of their role in prion infection and/or propagation"
Centre for Prions, University of Alberta, Edmonton, Alberta, Canada
"Contribution of oligomeric prion populations to phenotypic heterogeneity in variably protease-sensitive prionopathy (VPSPr) versus silent prions"
Department of Biomedical Sciences, University of Cagliari (UniCa), Italy
"Development of a blood and urine prion diagnostic test for human prion diseases using the Real Time QuIC assays"
Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
"Enzymatic PrP shedding in humans: Biomarker potential and therapeutic target"
Department of Pharmaceutical Sciences (DPS), University of Perugia-Italy
"Blocking the Neurotoxic Activities of Mutant Prion Proteins by a Novel Class of Therapeutic Agents"
National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
"Assessing the replication properties of prion protein aggregates found in archived formalin-fixed, paraffin embedded appendix tissue collected from the asymptomatic population by the highly sensitive in vitro prion amplification assay"
Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain
"Development and characterization of the fastest animal model able to propagate GSS prions faithfully"
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
"Prion protein aggregate size distribution drives clinical phenotype"
Laboratory of Persistent Viral Diseases (LPVD), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, Hamilton, MT
"Regional tropism of sporadic CJD subtypes in human brain organoids"
Department of Neurology. The University of Texas Health Science Center at Houston
"Development of a high throughput system for screening anti-prion molecules"
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH
"Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results"
National Prion Disease and Pathology Surveillance Center, Case Western Reserve University, University Hospitals, Cleveland, OH
"Examining copy number variants as a possible phenotype modifier in prion disease"
Department of Pathology, Case Western Reserve University, Cleveland, Ohio
"Assessing Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on CJD"
University of Trento, Italy
“Pharmacological Degraders for the Cellular Prion Protein”