University of Trento, Italy “Pharmacological Degraders for the Cellular Prion Protein”
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Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy "Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation"
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Public Health Agency of Canada and University of Manitoba "Detection and characterization of rare strains of sporadic Creutzfeldt-Jakob Disease using a suite of novel biological and biochemical tools"
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University of Modena and Reggio Emilia, Modena, Italy "Optimization of nanoparticle-mediated brain delivery of a tetracationic porphyrin with potent anti-prion activities"
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The Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Spain and German Center for Neurodegenerative Diseases "Implementation of a blood-based biomarker test for sporadic Creutzfeldt-Jakob in clinical practice"
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University College London (UCL) Institute of Prion Diseases "Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)"
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Centre for Prions and Protein Folding Diseases, University of Alberta, Canada "Strain-specific pathology and spread in prion organotypic slice culture assay infected with different strains of Creutzfeldt-Jakob Disease"
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University of Alberta, Centre for Prions and Protein Folding Diseases "Evaluating passive immunotherapy in prion-infected transgenic mice expressing human PrP"
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Rocky Mountain Laboratories, NIH/NIAID “Evaluation of new anti-prion drugs: from drug design to therapeutic efficacy against human prions in vitro, ex-vivo and in vivo”
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Case Western Reserve University “The RAP approach for effective prevention and treatment of prion diseases”
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Prion Research Center, Colorado State University “Use of Blood-borne Prion Amplification Assays for the Detection of Human Prion Diseases and Biomarker Assessment”
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Department of Neurology, The University of Texas Health Science Center at Houston “Exploring the zoonotic potential of porcine-derived materials from animals exposed to infectious prions”
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Istituto Superiore di Sanità, Dept. of Neuroscience, Rome “Investigating the influence of CYP4X1 gene on age at onset of CJD as potential preventive therapeutic approach”
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Washington University School of Medicine “The Contribution of Rare Variant and Copy-Number Variation to Risk of Sporadic CJD and Pleiotropy with Other Neurodegenerative Diseases”
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Broad Institute of MIT and Harvard “Assessing efficacy of zinc-finger repressors of prion protein as a therapeutic for prion disease”
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The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders; The University of Texas Health Science Center at Houston “Generating Recombinant Human Prions in Large Scale for Structural Studies”
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University of Alberta, Edmonton, Alberta, Canada “Evaluating prion vaccines in transgenic mouse models of familial prion diseases”
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Professor of Neurology, Harvard Medical School; and Translational Neurology Head of the Interdisciplinary Brain Center, Massachusetts General Hospital “Assessing long-term stability of cerebrospinal fluid PrP levels in genetic prion disease mutation carriers”
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Laboratory of Prion Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy “Nanoparticle-mediated brain delivery of a tetracationic porphyrin with potent anti-prion activities”
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National Institute of Allergy and Infectious Diseases, NIH “Cerebral neuronal dysfunction associated with human prion diseases”
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