Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
"Enzymatic PrP shedding in humans: Biomarker potential and therapeutic target"
Department of Pharmaceutical Sciences (DPS), University of Perugia-Italy
"Blocking the Neurotoxic Activities of Mutant Prion Proteins by a Novel Class of Therapeutic Agents"
National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
"Assessing the replication properties of prion protein aggregates found in archived formalin-fixed, paraffin embedded appendix tissue collected from the asymptomatic population by the highly sensitive in vitro prion amplification assay"
Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain
"Development and characterization of the fastest animal model able to propagate GSS prions faithfully"
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
"Prion protein aggregate size distribution drives clinical phenotype"
Laboratory of Persistent Viral Diseases (LPVD), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, Hamilton, MT
"Regional tropism of sporadic CJD subtypes in human brain organoids"
Department of Neurology. The University of Texas Health Science Center at Houston
"Development of a high throughput system for screening anti-prion molecules"
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH
"Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results"
National Prion Disease and Pathology Surveillance Center, Case Western Reserve University, University Hospitals, Cleveland, OH
"Examining copy number variants as a possible phenotype modifier in prion disease"
Department of Pathology, Case Western Reserve University, Cleveland, Ohio
"Assessing Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on CJD"
University of Trento, Italy
“Pharmacological Degraders for the Cellular Prion Protein”
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
"Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation"
Public Health Agency of Canada and University of Manitoba
"Detection and characterization of rare strains of sporadic Creutzfeldt-Jakob Disease using a suite of novel biological and biochemical tools"
University of Modena and Reggio Emilia, Modena, Italy
"Optimization of nanoparticle-mediated brain delivery of a tetracationic porphyrin with potent anti-prion activities"
The Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Spain and German Center for Neurodegenerative Diseases
"Implementation of a blood-based biomarker test for sporadic Creutzfeldt-Jakob in clinical practice"
University College London (UCL) Institute of Prion Diseases
"Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)"
Centre for Prions and Protein Folding Diseases, University of Alberta, Canada
"Strain-specific pathology and spread in prion organotypic slice culture assay infected with different strains of Creutzfeldt-Jakob Disease"
University of Alberta, Centre for Prions and Protein Folding Diseases
"Evaluating passive immunotherapy in prion-infected transgenic mice expressing human PrP"
Rocky Mountain Laboratories, NIH/NIAID
“Evaluation of new anti-prion drugs: from drug design to therapeutic efficacy against human prions in vitro, ex-vivo and in vivo”
Case Western Reserve University
“The RAP approach for effective prevention and treatment of prion diseases”