Contributed by:
This grant was established in 2015.
Research Grants Supported
Dr. Thomas Cunningham, 2023
MRC Prion Unit at UCL, Institute of Prion Diseases
Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention
Dr. Sarah Vascellari, 2023
Department of Biomedical Sciences, University of Cagliari (UniCa), Italy
Development of a blood and urine prion diagnostic test for human prion diseases using the Real Time QuIC assays
Jaime Noguez, PhD, 2022
Case Western Reserve University
"Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results"
Jason Thomas Duskey and Barbara Ruozi, PhD, 2021
University of Modena and Reggio Emilia, Modena, Italy
"Optimization of nanoparticle-mediated brain delivery of a tetracationic porphyrin with potent anti-prion activities"
Qingzhong Kong, PhD, 2020
Case Western Reserve University
“The RAP approach for effective prevention and treatment of prion diseases”
Gustavo Mostoslavsky, MD, PhD, 2019
Modeling Creutzfeldt-Jakob Disease Using Human iPSC-derived Neurons
Center for Regenerative Medicine, Boston University School of Medicine
David A. Harris, M.D., Ph.D., 2018
Highly Synergistic Combination Therapy for Prion Diseases
Department of Biochemistry, Boston University School of Medicine
Charles E. Mays, Ph.D., 2017
Treatment with a Non-Toxic, Self-Replicating Anti-Prion
University of Texas-Houston
Byron Caughey, Ph.D., 2016
Antisense Oligonucleotides to Delay or Prevent Onset of Prion Disease in Mice
National Institute of Allergy and Infectious Diseases, National Institute of Health
Hamilton, Montana
Zuzana Krejciova, Ph.D., 2016
Human Stem Cell Derived Neural Models for sCJD Prion Propagation and Drug Discovery
Institute for Neurodegenerative Diseases, University of California
San Francisco, California
Wen-Quan Zou, M.D., Ph.D., 2015
Developing Therapeutics for CJD Using Patient-Specific iPSC-Derived Neurons
National Prion Disease Pathology Surveillance Center, Case Western Reserve University School of Medicine
Cleveland, Ohio