Form: Sporadic CJD (sCJD)
Distinguishing Features: Affects mainly people over the age of 60. Common symptoms include ataxia and dementia. Short course. Upon tissue examination there is spongiform change, but plaques are rarely present.
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Form: Sporadic Fatal Insomnia (sFI)
Distinguishing Features: Has clinical and histopathologic features indistinguishable from those of Fatal Familial Insomnia (FFI), but does not have the mutation on the prion gene that characterizes FFI.
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