Contributed by:
This grant was established in 2015.
Research Grants Supported
Dr. Thomas Cunningham, 2023
MRC Prion Unit at UCL, Institute of Prion Diseases
Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention
Jason C. Bartz, Ph.D. and Dr. Yuan, Ph.D., 2023
Creighton University
"Detection of residual prions from decontaminated medical and laboratory surfaces"
Jaime Noguez, PhD, 2022
Case Western Reserve University
"Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results"
Cathryn Haigh, PhD, 2022
Rocky Mountain Laboratories
"Regional tropism of sporadic CJD subtypes in human brain organoids"
Brooke Sadler, PhD, and Gabriel Haller, PhD, 2020
Washington University School of Medicine
“The Contribution of Rare Variant and Copy-Number Variation to Risk of Sporadic CJD and Pleiotropy with Other Neurodegenerative Diseases”
Qingzhong Kong, PhD, 2020
Case Western Reserve University
“The RAP approach for effective prevention and treatment of prion diseases”
Dr. Graham S. Jackson, 2019
Development of a quantitative, real-time Protein-Misfolding by Cyclic Amplification (PMCA) reaction
Medical Research Council (MRC) Prion Unit at University College London
Jiyan Ma, PhD, 2019
Determining the therapeutic potential of anti-PrP nanobody
Professor, Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI
Allison Kraus, Ph.D., 2018
Investigation of Prion Inactivation by Reactive Oxygen Species in Vivo
Rocky Mountain Laboratories, Montana
Rodrigo Morales, Ph.D., 2018
Systematic Evaluation of the Zoonotic Potential of Different CWD Isolates
Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, Department of Neurology, University of Texas-Houston Medical School
Stéphane Haik, M.D., Ph.D., 2017
Worms: A Novel Genetic Model for Therapeutic Research in Prion Disease
Alzheimer’s and Prion Diseases Lab at the Brain & Spine Institute (ICM) of the Salpêtrière Hospital, Sorbonne Université,
Paris, France
Wen-Quan Zou, M.D., Ph.D., 2017
Assessing Prion Infectivity in the Skin of Sporadic CJD Patients
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, Ohio
Valerie Sim, M.D., FRCPC, 2016
Combination Therapies for Human Prion Disease
Department of Medicine, University of Alberta
Edmonton, Alberta, Canada
Christina Sigurdson, DVM, Ph.D., 2015
Mechanisms of Selective Neuronal Vulnerability in Human Prion Disease
University of California, San Diego