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2021 Presentations

Watch Highlights from sessions at the 2021 Virtual CJD Foundation Family Conference:

Hear from Brian Appleby, MD, Medical Director, CJD Foundation, and Director, NPDPSC; Inga Zerr, MD, German Center for Neurodegenerative Diseases – National Reference Ctr. for Surveillance of Transmissible Spongiform Encephalopathies, Germany; Alberto Bizzi, MD, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; and Simon Mead, PhD, University College London (UCL) Institute of Prion Diseases discuss this during a research grant recipients panel discussion.

Ryan Maddox, PhD, Epidemiologist, Prion and Public Health Office Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention (CDC)

Watch Presentation: 2021 CDC Report

Introduction by: Dr. Pierluigi Gambetti
Brian Appleby, MD, Medical Director, CJD Foundation, and Director, National Prion Disease Pathology Surveillance Center

Watch Presentation: Keynote Address: A Historical Appraisal Of The Field Of Prion Diseases: What We’ve Learned And Why We Should Be Optimistic

Brian Appleby, MD, Director of National Prion Disease Pathology Surveillance Center
Gregory Day, MD, MSc, Dept. of Neurology, Mayo Clinic
Michael Geschwind, MD, PhD, Memory and Aging Center, University of California, San Francisco (UCSF)
Moderator: Prof. Richard Knight, Emeritus Professor of Clinical Neurology, CCBS, University of Edinburgh

Watch Presentation: Diagnosis And Caregiving For CJD Patients

Brian Appleby, MD, Medical Director, CJD Foundation, and Director, National Prion Disease Pathology Surveillance Center

Watch Presentation: National Prion Disease Pathology Surveillance Center Update

CJD Foundation Research Grant Recipient Reports Panel 1

  • Inga Zerr, MD, German Center for Neurodegenerative Diseases – National Reference Ctr. for Surveillance of Transmissible Spongiform Encephalopathies, Germany
    Implementation of a blood-based biomarker test for sporadic Creutzfeldt-Jakob in clinical practice
  • Alberto Bizzi, MD, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
    Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation
  • Simon Mead, PhD, University College London (UCL) Institute of Prion Diseases
    Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)
  • Moderator: Brian Appleby, MD, Medical Director, CJD Foundation, and Director, National Prion Disease Pathology Surveillance Center

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CJD Foundation Research Grant Recipient Reports Panel 2

  • Valerie Sim, MD, FRCPC, Centre for Prions and Protein Folding Diseases, University of Alberta, Canada
    Strain-specific pathology and spread in prion organotypic slice culture assay infected with different strains of Creutzfeldt-Jakob Disease
  • Stephanie Booth, PhD, Public Health Agency of Canada and University of Manitoba
    Detection and characterization of rare strains of sporadic Creutzfeldt-Jakob Disease using a suite of novel biological and biochemical tools
  • Moderator: Joel Watts

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CJD Foundation Research Grant Recipient Reports Panel 3

  • Emiliano Biasini, PhD, Dulbecco Telethon Laboratory of Prions and Amyloids, Department of Cellular, Computational & Integrative Biology (CIBIO), University of Trento, Italy 
    Pharmacological Degraders for the Cellular Prion Protein
  • Jason Thomas Duskey, PhD, University of Modena and Reggio Emilia, Modena, Italy 
    Optimization of nanoparticle-mediated brain delivery of a tetracationic porphyrin with potent anti-prion activities
  • Holger Wille, PhD, University of Alberta, Centre for Prions and Protein Folding Diseases
    Evaluating passive immunotherapy in prion-infected transgenic mice expressing human PrP
  • Moderator: Prof. Richard Knight, Emeritus Professor of Clinical Neurology, CCBS, University of Edinburgh

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