The Andy Lewis Memorial Grant

Contributed by: His Daughters, Extended Family, and Friends

This grant was established in 2022.

Research Grants Supported

Simon Mead, PhD

Grant Title: DNA Extraction for Global Genome-Wide Association Studies (GWAS) in Creutzfeldt-Jakob Disease

Location: MRC Prion Unit and National Prion Clinic, University College London (UCL) Institute of Prion Diseases

Grant Year: 2026

Thomas J. Trainer

Grant Title: The structural basis of prion-induced synaptotoxicity

Location: Imperial College London (ICL)

Grant Year: 2026

Vanessa Laversenne, PhD

Grant Title: Hypomorphic low PrP expressing mice as models for prion replication and native function

Location: Broad Institute of MIT and Harvard

Grant Year: 2026

Jakub Soukup, PhD

Grant Title: Higher-resolution visualization of prion fibrils in neurons and extracellular vesicles using state-of-the-art Cryo-TEM and FIB-SEM imaging

Location: Rocky Mountain Laboratories, NIAID, NIH

Grant Year: 2025

Dr. Pei Ying Lee

Grant Title: Assessing retinal function as a potential early biomarker for Creutzfeldt-Jakob Disease (CJD)

Location: Department of Optometry and Vision Sciences, The University of Melbourne

Grant Year: 2025

Jose Andres Alepuz Guillen, PhD

Grant Title: Characterization of synaptic abnormalities in iPSC-derived neurons from E200K carriers

Location: Boston University Chobanian & Avedisian School of Medicine

Grant Year: 2025

Dr. Adriano Aguzzi and Davide Caredio

Grant Title:
Investigation of Glycoprotein Nonmetastatic Melanoma protein B (GPNMB) as potential therapeutic target in Prion Diseases

Location:
University of Zurich

Grant Year: 2024

Dr. Thomas Cunningham and Elizabeth Hill

Grant Title:
Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention

Location:
MRC Prion Unit at UCL, Institute of Prion Diseases, London

Grant Year: 2023

Hermann Clemens Altmeppen, PhD

Grant Title:
Enzymatic PrP shedding in humans: Biomarker potential and therapeutic target

Location:
Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Grant Year: 2022