General Practitioners should be aware of Creutzfeldt-Jakob Disease, although they may never see a case. A prompt referral to a neurologist should follow observation of any suspicious pattern of symptoms.
A radiology technique that uses magnetism, radio waves and a computer to produce non-invasive, high quality images of internal structures of the body. An MRI is painless, does not use x-ray radiation and is a powerful tool for delineating brain structure.
MRI findings may be bilateral or unilateral, and symmetric or asymmetric. They can include:
An MRI technique that can be used to help diagnose CJD.
Flat metal discs (electrodes) placed on the patient’s scalp detect and record the patterns of electrical activity generated by the brain. Can help in diagnosing CJD.
An amplification technique to multiply prions. PMCA technology has been used in research to understand the molecular mechanism of prion replication, the nature of the infectious agent, the phenomenon of prion strains and species barrier, the effect of cellular components, to detect PrPSc in tissues and biological fluids and to screen for inhibitors against prion replication.
Blood, urine, nasal brushings, skin.
This website was made possible by a generous donation from Cookie Stivison, in memory of her husband Tom Stivison, and a grant from the Centers for Disease Control and Prevention.