Debbie Yobs
President and Executive Director
Morris Plains, New Jersey
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- Supporting Families Affected by Prion Disease
This study will assess the use of simple, rapid, specific and highly sensitive assays to detect blood-borne prions. Early detection of prion disease will provide a biomarker for prognostication and development of therapeutic trials.
Dr. Mathiason is Associate Professor of Pathobiology and Director of the Office of Vice President for Research (OVPR) Program for Research and Scholarly Excellence (PRSE)- Infectious Disease and Rapid Response Network. Dr. Mathiason’s research focuses on the role blood and maternal infections play in disease pathogenesis and transmission dynamics. Her laboratory combines use of native and rodent in vivo hosts with highly sensitive in vitro assays to assimilate an understanding of the biological mechanisms associated with covert transmission of infectious agents. The intent of these works is to provide basic science principles for continued efforts to mitigate infectious agents via preventative, therapeutic and vaccine therapies.
President and Executive Director
Morris Plains, New Jersey
Grant Title: Investigating the role of BLOC-1 complex in prion disease
Location: Institute for the Science of the Aging Brain (ISAB), St. Gallen, Switzerland
Grant Year: 2026
Grant Title: DNA Extraction for Global Genome-Wide Association Studies (GWAS) in Creutzfeldt-Jakob Disease
Location: MRC Prion Unit and National Prion Clinic, University College London (UCL) Institute of Prion Diseases
Grant Year: 2026
Grant Title: The structural basis of prion-induced synaptotoxicity
Location: Imperial College London (ICL)
Grant Year: 2026
Grant Title: New strains, new risks: evaluating the host range and zoonotic potential of CWD prion strains
Location: The University of Texas Health Science Center at Houston
Grant Year: 2026
Grant Title: Characterizing Early Synaptic Dysfunction in Human Prion Disease Using a Human iPSC-Derived Neuronal Model
Location: University of California, San Diego
Grant Year: 2026
Grant Title: Haematopoietic stem cell gene therapy as a novel therapeutic for CNS prion disease
Location: The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh
Grant Year: 2026