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Alyssa Block, PhD

Grant Title: Refined transgenetic approaches to investigate selective adaptation of human prions during intracranial and peripheral transmissions

Location: Prion Research Center, Colorado State University

Grant Year: 2025

Jose Andres Alepuz Guillen, Ph.D.

Grant Title: Characterization of synaptic abnormalities in iPSC-derived neurons from E200K carriers

Location: Boston University Chobanian & Avedisian School of Medicine

Grant Year: 2025

Gianluigi Zanusso, MD, PhD

Grant Title: Multi-center assessment of olfactory swab procedure performed by non-otolaryngologists for improving and simplifying human prion disease diagnosis

Location: Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy

Grant Year: 2025

Joel Watts, PhD

Grant Title: Engineered biosensors for improved prion detection

Location: Tanz Centre for Research in Neurodegenerative Diseases and Department of Biochemistry, University of Toronto

Grant Year: 2025

Jakub Soukup, PhD

Grant Title: Higher-resolution visualization of prion fibrils in neurons and extracellular vesicles using state-of-the-art Cryo-TEM and FIB-SEM imaging

Location: Rocky Mountain Laboratories, NIAID, NIH

Grant Year: 2025

Dr. Szymon W. Manka

Grant Title: Engineering human cells to propagate fluorescent prions for live monitoring of prion infection and high-resolution in situ prion structure determination

Location: Imperial College London, Faculty of Medicine, Department of Infectious Disease,
Synthetic and Structural Biology Section

Grant Year: 2025

Dr. Pei Ying Lee

Grant Title: Assessing retinal function as a potential early biomarker for Creutzfeldt-Jakob Disease (CJD)

Location: Department of Optometry and Vision Sciences, The University of Melbourne

Grant Year: 2025

Ignazio Cali, PhD

Grant Title: Investigating prion protein seeding activity in non-prion disease dementia

Location: Department of Medicine and Surgery, University Kore of Enna, Italy; Adjunct Assistant Professor in the Department of Pathology, at Case Western Reserve University (CWRU); Associate Director at National Prion Disease Pathology Surveillance Center (NPDPSC), Cleveland, OH

Grant Year: 2025