Contributed by: The Glavan and Gallagher families
This grant was established in 2022.
Grant Title:
Blocking the Neurotoxic Activities of Mutant Prion Proteins by a Novel Class of Therapeutic Agents
Location:
Department of Pharmaceutical Sciences (DPS), University of Perugia-Italy
Grant Year: 2022
Grant Title:
Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention
Location:
MRC Prion Unit at UCL, Institute of Prion Diseases, London
Grant Year: 2023
Grant Title:
Exploring the efficacy of dominant negative protein-based gene therapy for different prion diseases: in vivo proof-of-concept study
Location:
Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain
Grant Year: 2024
Grant Title:
Development of ADAM8-based Gene Therapy for CJD
Location:
NPDPSC, Case Western Reserve University
Grant Year: 2024
Grant Title: Characterization of synaptic abnormalities in iPSC-derived neurons from E200K carriers
Location: Boston University Chobanian & Avedisian School of Medicine
Grant Year: 2025
Grant Title: Engineering human cells to propagate fluorescent prions for live monitoring of prion infection and high-resolution in situ prion structure determination
Location: Imperial College London, Faculty of Medicine, Department of Infectious Disease,
Synthetic and Structural Biology Section
Grant Year: 2025
Grant Title: Assessing efficacy of a PrP-lowering Molecular Gate as a therapeutic for prion disease
Location: Gate Bioscience
Grant Year: 2025
Grant Title: Engineered biosensors for improved prion detection
Location: Tanz Centre for Research in Neurodegenerative Diseases and Department of Biochemistry, University of Toronto
Grant Year: 2025
Grant Title: Multi-center assessment of olfactory swab procedure performed by non-otolaryngologists for improving and simplifying human prion disease diagnosis
Location: Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy
Grant Year: 2025