Grant Title:
The RAP approach for effective prevention and treatment of prion diseases
Location:
Case Western Reserve University
Grant Year:
2020
Grant Title:
Evaluating passive immunotherapy in prion-infected transgenic mice expressing human PrP
Location:
University of Alberta, Edmonton, Alberta, Canada
Grant Year: 2021
Grant Title: Development and characterization of the fastest animal model able to propagate GSS prions faithfully
Location:
Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain
Grant Year: 2022
Grant Title:
Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention
Location:
MRC Prion Unit at UCL, Institute of Prion Diseases, London
Grant Year: 2023
Grant Title: Assessing long-term stability of cerebrospinal fluid PrP levels in genetic prion disease mutation carriers
Location: Professor of Neurology, Harvard Medical School; and Translational Neurology Head of the Interdisciplinary Brain Center, Massachusetts General Hospital
Grant Year: 2019
Grant Title:
“Isolation and Strain-Specific Characterization of Pathogenic CJD Prion Particles”
Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
Grant Year:
2018
Grant Title:
Worms: A novel genetic model for therapeutic research in prion disease
Location:
Alzheimer’s and Prion diseases Lab at the Brain & Spine Institute (ICM) of the Salpêtrière Hospital, Sorbonne Université, Paris, France
Grant Year:
2017
Grant Title:
A new anti-prion compound that reduces PrPc levels and inhibits PrPsc replication. [Awaiting permission to release from Dr. Chiesa.]
Location:
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
Grant Year: 2016
Grant Title:
The Role of Cellular Chaperones and the Unfolded Protein Response in Gerstmann-Sträussler-Scheinker Syndrome
Location:
Prion Research Center, Colorado State University
Grant Year:
2015
Grant Title:
Bridging the pre-clinical gap for a small brain-penetrant molecule that reduces PrPC levels
Location:
Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto
Grant Year: 2024
Grant Title: Assessing efficacy of a PrP-lowering Molecular Gate as a therapeutic for prion disease
Location: Gate Bioscience
Grant Year: 2025