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The Jeffrey A. Smith Memorial Research Grant

Contributed by: The Jeffrey and Mary Smith Family Foundation; Zoë Smith Jaye and Jenny Smith Unruh; and Mary Smith

Established in 2015

Research Grants Supported

Ignazio Cali, PhD

Grant Title:
Investigating prion protein seeding activity in Alzheimer’s disease and chronic traumatic encephalopathy

Location:
Department of Pathology, Case Western Reserve University

Grant Year: 2023

Leonardo Cortez, PhD & Valerie Sim, MD, FRCPC

Grant Title:
Prion protein aggregate size distribution drives clinical phenotype

Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada

Grant Year: 2022

Valerie Sim, MD, FRCPC

Grant Title:
Strain-specific pathology and spread in prion organotypic slice culture assay infected with different strains of Creutzfeldt-Jakob Disease

Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Canada

Grant Year: 2021

Simon Mead, PhD

Grant Title:
Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)

Location:
University College London (UCL) Institute of Prion Diseases

Grant Year: 2021

Alberto Bizzi, MD

Grant Title:
Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation

Location:
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy

Grant Year: 2021

Fei Wang, PhD

Grant Title:
Generating Recombinant Human Prions in Large Scale for Structural Studies

Location:
The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders; The University of Texas Health Science Center at Houston

Grant Year: 2020