Rodrigo Morales, PhD

Grant Title:
Development of a high throughput system for screening anti-prion molecules
Location:
University of Texas, Houston, TX
Grant Year: 2022
Hermann Clemens Altmeppen, PhD

Grant Title:
Enzymatic PrP shedding in humans: Biomarker potential and therapeutic target
Location:
Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Grant Year: 2022
Maria Letizia Barreca, PhD

Grant Title:
Blocking the Neurotoxic Activities of Mutant Prion Proteins by a Novel Class of Therapeutic Agents
Location:
Department of Pharmaceutical Sciences (DPS), University of Perugia-Italy
Grant Year: 2022
Marcelo Barria, PhD & Alison Green, PhD

Grant Title:
Assessing the replication properties of prion protein aggregates found in archived formalin-fixed, paraffin embedded appendix tissue collected from the asymptomatic population by the highly sensitive in vitro prion amplification assay.
Location:
National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
Grant Year: 2022
JoaquÃn Castilla, PhD

Grant Title: Development and characterization of the fastest animal model able to propagate GSS prions faithfully
Location:
Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain
Grant Year: 2022
Leonardo Cortez, PhD & Valerie Sim, MD, FRCPC

Grant Title:
Prion protein aggregate size distribution drives clinical phenotype
Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
Grant Year: 2022
Cathryn Haigh, PhD

Grant Title:
“Regional tropism of sporadic CJD subtypes in human brain organoids”
Location:
Laboratory of Neurological Infections and Immunity (LNII), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, Hamilton, MT
Grant Year: 2022
Jaime Noguez

Grant Title:
Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results
Location:
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH
Grant Year: 2022
Shashirekha Shetty, PhD

Grant Title:
Examining copy number variants as a possible phenotype modifier in prion disease
Location:
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, University Hospitals, Cleveland, OH
Grant Year: 2022
Zerui Wang, MD, PhD and Katsumi Doh-ura, MD, PhD

Grant Title:
Assessing Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on CJD
Location:
Department of Pathology, Case Western Reserve University, Cleveland, Ohio
Grant Year: 2022