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Dr. Emmanuelle Vire

Grant Title: Investigating the relevance of blood DNA methylation signals for disease management in CJD

Location: Medical Research Council (MRC) Prion Unit at University College London

Grant Year: 2019

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This study will explore how processes that regulate gene expression can be dramatically deregulated in human diseases. Understanding how, when, and where can tremendously impact on disease management, prevention and treatment. This project will look at one of these processes: DNA methylation (the addition of methyl marks to the DNA molecules) in patients with genetic prion diseases. The aim is to correlate these marks with disease onset and to develop markers to track the disease in patients, with the purpose of making clinical trials more feasible.

Recipient of:

The Strides for CJD Research Grant

Contributed by: The Families of the CJD Foundation

Funds raised by the annual Strides for CJD run/walk have been applied to research grants awarded since 2016.