Dr. Ignazio Cali received his doctoral degree (Ph.D.) from the University of Campania “Luigi Vanvitelli.” In 2015 he carried out his thesis work at Case Western Reserve University. Currently, Dr. Cali is an Associate Professor at University Kore of Enna and Associate Director of the National Prion Disease Pathology Surveillance Center (NPDPSC). His main research interests focus on understanding the molecular basis of phenotypic expression in comorbid neurodegenerative diseases, such as prion diseases and Alzheimer’s disease or prion diseases and chronic traumatic encephalopathy. This research aims at investigating the reciprocal impact that the two or more pathological proteins have on each other, and the pathological consequences of the interactions between different pathogenic proteins. Dr. Cali has published nearly 50 articles on human prion diseases, and animal models of the disease.