Contributed by: The Jeffrey and Mary Smith Family Foundation; Zoë Smith Jaye and Jenny Smith Unruh; and Mary Smith
Established in 2015
Grant Title: Engineering human cells to propagate fluorescent prions for live monitoring of prion infection and high-resolution in situ prion structure determination
Location: Imperial College London, Faculty of Medicine, Department of Infectious Disease,
Synthetic and Structural Biology Section
Grant Year: 2025
Grant Title:
Investigating prion protein seeding activity in Alzheimer’s disease and chronic traumatic encephalopathy
Location:
Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH
Grant Year: 2023
Grant Title:
Prion protein aggregate size distribution drives clinical phenotype
Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
Grant Year: 2022
Grant Title:
Strain-specific pathology and spread in prion organotypic slice culture assay infected with different strains of Creutzfeldt-Jakob Disease
Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Canada
Grant Year: 2021
Grant Title:
Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)
Location:
University College London (UCL) Institute of Prion Diseases
Grant Year: 2021
Grant Title:
Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation
Location:
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
Grant Year: 2021
Grant Title:
Generating Recombinant Human Prions in Large Scale for Structural Studies
Location:
The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders; The University of Texas Health Science Center at Houston
Grant Year: 2020
Grant Title:
Assessing efficacy of zinc-finger repressors of prion protein as a therapeutic for prion disease
Location:
Broad Institute of MIT and Harvard
Grant Year: 2020
Grant Title:
Exploring the zoonotic potential of porcine-derived materials from animals exposed to infectious prions
Location:
Department of Neurology, The University of Texas Health Science Center at Houston
Grant Year: 2020
Grant Title:
Evaluation of new anti-prion drugs: from drug design to therapeutic efficacy against human prions in vitro, ex-vivo and in vivo
Location:
Rocky Mountain Laboratories, NIH/NIAID
Grant Year: 2020
This website was made possible by a generous donation from Cookie Stivison, in memory of her husband Tom Stivison, and a grant from the Centers for Disease Control and Prevention.
