Grant Title: Multi-center assessment of olfactory swab procedure performed by non-otolaryngologists for improving and simplifying human prion disease diagnosis
Location: Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy
Grant Year: 2025
Grant Title: Engineered biosensors for improved prion detection
Location: Tanz Centre for Research in Neurodegenerative Diseases and Department of Biochemistry, University of Toronto
Grant Year: 2025
Grant Title: Higher-resolution visualization of prion fibrils in neurons and extracellular vesicles using state-of-the-art Cryo-TEM and FIB-SEM imaging
Location: Rocky Mountain Laboratories, NIAID, NIH
Grant Year: 2025
Grant Title: Assessing retinal function as a potential early biomarker for Creutzfeldt-Jakob Disease (CJD)
Location: Department of Optometry and Vision Sciences, The University of Melbourne
Grant Year: 2025
Grant Title: Characterization of synaptic abnormalities in iPSC-derived neurons from E200K carriers
Location: Boston University Chobanian & Avedisian School of Medicine
Grant Year: 2025
Grant Title: Investigating prion protein seeding activity in non-prion disease dementia
Location: Department of Medicine and Surgery, University Kore of Enna, Italy; Adjunct Assistant Professor in the Department of Pathology, at Case Western Reserve University (CWRU); Associate Director at National Prion Disease Pathology Surveillance Center (NPDPSC), Cleveland, OH
Grant Year: 2025
Grant Title: Refined transgenetic approaches to investigate selective adaptation of human prions during intracranial and peripheral transmissions
Location: Prion Research Center, Colorado State University
Grant Year: 2025
Grant Title:
Human stem cell derived neural models for sCJD prion propagation and drug discovery
Location:
Institute for Neurodegenerative Diseases, University of California, San Francisco
Grant Year:
2016
Grant Title:
A new anti-prion compound that reduces PrPc levels and inhibits PrPsc replication. [Awaiting permission to release from Dr. Chiesa.]
Location:
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
Grant Year: 2016
Grant Title:
Assessing Prions in Sporadic CJD Patients
Location:
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, Ohio
Grant Year:
2017
Grant Title:
RT-QuIC assay on olfactory brushings in asymptomatic carriers of E200K mutation: An explorative study for establishing when a preventive therapy should be started
Location:
University of Verona, Italy
Grant Year:
2017
Grant Title:
Worms: A novel genetic model for therapeutic research in prion disease
Location:
Alzheimer’s and Prion diseases Lab at the Brain & Spine Institute (ICM) of the Salpêtrière Hospital, Sorbonne Université, Paris, France
Grant Year:
2017
Grant Title:
“Systematic Evaluation of the Zoonotic Potential of Different CWD Isolates”
Location:
Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, Department of Neurology, University of Texas-Houston Medical School
Grant Year:
2018
Grant Title:
“Isolation and Strain-Specific Characterization of Pathogenic CJD Prion Particles”
Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada
Grant Year:
2018
Grant Title:
“Investigating the Potential of the Neuroprotective N1 Fragment of the Prion Protein as a New Treatment Against Prion Diseases”
Location:
Institute of Neuropathology, University Medical Center – Eppendorf, Hamburg, Germany
Grant Year:
2018
Grant Title:
Investigating the relevance of blood DNA methylation signals for disease management in CJD
Location:
Medical Research Council (MRC) Prion Unit at University College London
Grant Year: 2019
Grant Title: Development of a quantitative, real-time Protein-Misfolding by Cyclic Amplification (PMCA) reaction
Location: Medical Research Council (MRC) Prion Unit at University College London
Grant Year: 2019
Grant Title:
Cerebral neuronal dysfunction associated with human prion diseases
Location:
National Institute of Allergy and Infectious Diseases, NIH
Grant Year: 2019
Grant Title:
“Use of Blood-borne Prion Amplification Assays for the Detection of Human Prion Diseases and Biomarker Assessment”
Location:
Prion Research Center, Colorado State University
Grant Year:
2020
Grant Title:
The identification of PrPSc interaction partners and the characterization of their role in prion infection and/or propagation
Location:
Instructor, Department of Biochemistry, Boston University School of Medicine, Boston, MA
Grant Year: 2023
Grant Title:
“High-resolution structure determination of MM1 and MM2 sCJD prions”
Location:
Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH
Grant Year: 2023
Grant Title:
Risk of cancer from reduced expression of PrPC-implications for prion disease treatment”
Location:
Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Victoria, Australia
Grant Year: 2023
Grant Title:
Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention
Location:
MRC Prion Unit at UCL, Institute of Prion Diseases, London
Grant Year: 2023
Grant Title:
Detection of residual prions from decontaminated medical and laboratory surfaces
Location:
School of Medicine, Creighton University, Omaha, NE
Grant Year: 2023
Grant Title:
Development of a high throughput system for screening anti-prion molecules
Location:
University of Texas, Houston, TX
Grant Year: 2022
Grant Title: Development and characterization of the fastest animal model able to propagate GSS prions faithfully
Location:
Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain
Grant Year: 2022
Grant Title:
Evaluating prion vaccines in transgenic mouse models of familial prion diseases
Location:
University of Alberta, Edmonton, Alberta, Canada
Grant Year: 2021
Grant Title:
Strain-specific pathology and spread in prion organotypic slice culture assay infected with different strains of Creutzfeldt-Jakob Disease
Location:
Centre for Prions and Protein Folding Diseases, University of Alberta, Canada
Grant Year: 2021
Grant Title:
Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)
Location:
University College London (UCL) Institute of Prion Diseases
Grant Year: 2021
Grant Title:
Implementation of a blood-based biomarker test for sporadic Creutzfeldt-Jakob in clinical practice”
Location:
The Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Spain and German Center for Neurodegenerative Diseases
Grant Year:
2021
Grant Title:
Optimization of nanoparticle-mediated brain delivery of a tetracationic porphyrin with potent anti-prion activities
Location:
University of Modena and Reggio Emilia, Modena, Italy
Grant Year: 2021
Grant Title:
Detection and characterization of rare strains of sporadic Creutzfeldt-Jakob Disease using a suite of novel biological and biochemical tools
Location:
Public Health Agency of Canada and University of Manitoba.
Grant Year: 2021
Grant Title:
Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation
Location:
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
Grant Year: 2021
Grant Title:
Pharmacological Degraders for the Cellular Prion Protein
Location:
University of Trento, Italy
Grant Year:
2021
Grant Title:
Generating Recombinant Human Prions in Large Scale for Structural Studies
Location:
The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders; The University of Texas Health Science Center at Houston
Grant Year: 2020
Grant Title:
Assessing efficacy of zinc-finger repressors of prion protein as a therapeutic for prion disease
Location:
Broad Institute of MIT and Harvard
Grant Year: 2020
Grant Title:
Exploring the zoonotic potential of porcine-derived materials from animals exposed to infectious prions
Location:
Department of Neurology, The University of Texas Health Science Center at Houston
Grant Year: 2020
Grant Title:
The RAP approach for effective prevention and treatment of prion diseases
Location:
Case Western Reserve University
Grant Year:
2020
Grant Title:
Evaluation of new anti-prion drugs: from drug design to therapeutic efficacy against human prions in vitro, ex-vivo and in vivo
Location:
Rocky Mountain Laboratories, NIH/NIAID
Grant Year: 2020
This website was made possible by a generous donation from Cookie Stivison, in memory of her husband Tom Stivison, and a grant from the Centers for Disease Control and Prevention.
