
Holger Wille, PhD
Grant Title:
Evaluating prion vaccines in transgenic mouse models of familial prion diseases
Location:
University of Alberta, Edmonton, Alberta, Canada
Grant Year: 2020
Grant Title:
Evaluating prion vaccines in transgenic mouse models of familial prion diseases
Location:
University of Alberta, Edmonton, Alberta, Canada
Grant Year: 2020
Grant Title: Multi-center assessment of olfactory swab procedure performed by non-otolaryngologists for improving and simplifying human prion disease diagnosis
Location: Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy
Grant Year: 2025
Grant Title:
“Assessing long-term stability of The CJD Foundations 2009 Research Grant Renewal: Comparative Study of Prions Associated with Iatrogenic and Sporadic Creutzfeldt-Jakob Disease: An Update
Location:
Department of Pathology, Case Western Reserve University; Associate Director of National Prion Disease Pathology Surveillance Center, Cleveland, Ohio
Grant Year:
2009
Grant Title:
Etiology of Sporadic CJD: Somatic Mutations of the Human Prion Protein Gene in Brain Cells
Location:
The National Prion Disease Pathology Surveillance Center, Cleveland, Ohio
Grant Year:
2009
Grant Title:
Targeting the endogenous proteolytic processing of PrPc as a therapeutic strategy against prion diseases
Location:
Institute of Neuropathology, University Medical Center Eppendorf
Grant Year:
2016
Grant Title:
“Systematic Evaluation of the Zoonotic Potential of Different CWD Isolates”
Location:
Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, Department of Neurology, University of Texas-Houston Medical School
Grant Year:
2018
Grant Title:
Determining the therapeutic potential of anti-PrP nanobody
Location: Professor, Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI
Grant Year: 2019
Grant Title:
Cerebral neuronal dysfunction associated with human prion diseases
Location:
National Institute of Allergy and Infectious Diseases, NIH
Grant Year: 2019
Grant Title:
“Use of Blood-borne Prion Amplification Assays for the Detection of Human Prion Diseases and Biomarker Assessment”
Location:
Prion Research Center, Colorado State University
Grant Year:
2020
Grant Title:
The identification of PrPSc interaction partners and the characterization of their role in prion infection and/or propagation
Location:
Instructor, Department of Biochemistry, Boston University School of Medicine, Boston, MA
Grant Year: 2023
Grant Title:
“High-resolution structure determination of MM1 and MM2 sCJD prions”
Location:
Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH
Grant Year: 2023
Grant Title:
Risk of cancer from reduced expression of PrPC-implications for prion disease treatment”
Location:
Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Victoria, Australia
Grant Year: 2023
Grant Title:
Detection of residual prions from decontaminated medical and laboratory surfaces
Location:
School of Medicine, Creighton University, Omaha, NE
Grant Year: 2023
Grant Title:
Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results
Location:
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH
Grant Year: 2022
Grant Title:
Evaluating passive immunotherapy in prion-infected transgenic mice expressing human PrP
Location:
University of Alberta, Edmonton, Alberta, Canada
Grant Year: 2021
Grant Title:
Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)
Location:
University College London (UCL) Institute of Prion Diseases
Grant Year: 2021
Grant Title:
Implementation of a blood-based biomarker test for sporadic Creutzfeldt-Jakob in clinical practice”
Location:
The Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Spain and German Center for Neurodegenerative Diseases
Grant Year:
2021
Grant Title:
Detection and characterization of rare strains of sporadic Creutzfeldt-Jakob Disease using a suite of novel biological and biochemical tools
Location:
Public Health Agency of Canada and University of Manitoba.
Grant Year: 2021
Grant Title:
Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation
Location:
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
Grant Year: 2021
Grant Title:
Pharmacological Degraders for the Cellular Prion Protein
Location:
University of Trento, Italy
Grant Year:
2021
Grant Title:
Generating Recombinant Human Prions in Large Scale for Structural Studies
Location:
The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders; The University of Texas Health Science Center at Houston
Grant Year: 2020
Grant Title:
Assessing efficacy of zinc-finger repressors of prion protein as a therapeutic for prion disease
Location:
Broad Institute of MIT and Harvard
Grant Year: 2020
Grant Title:
The RAP approach for effective prevention and treatment of prion diseases
Location:
Case Western Reserve University
Grant Year:
2020
Grant Title:
Evaluation of new anti-prion drugs: from drug design to therapeutic efficacy against human prions in vitro, ex-vivo and in vivo
Location:
Rocky Mountain Laboratories, NIH/NIAID
Grant Year: 2020
This website was made possible by a generous donation from Cookie Stivison, in memory of her husband Tom Stivison, and a grant from the Centers for Disease Control and Prevention.