The CJD Foundation Grant

Contributed by: The Families of the CJD Foundation

Funds donated by supporters of the CJD Foundation have been applied to research grants awarded since 2009.

Research Grants Supported

Wen-Quan Zou, M.D., Ph.D.

Grant Title:
“Assessing long-term stability of The CJD Foundations 2009 Research Grant Renewal: Comparative Study of Prions Associated with Iatrogenic and Sporadic Creutzfeldt-Jakob Disease: An Update

Location:
Department of Pathology, Case Western Reserve University; Associate Director of National Prion Disease Pathology Surveillance Center, Cleveland, Ohio

Grant Year:
2009

Qingzhong Kong, Ph.D.

Grant Title:
Etiology of Sporadic CJD: Somatic Mutations of the Human Prion Protein Gene in Brain Cells

Location:
The National Prion Disease Pathology Surveillance Center, Cleveland, Ohio

Grant Year:
2009

Dr. Hermann Clemens Altmeppen

Grant Title:
Targeting the endogenous proteolytic processing of PrPc as a therapeutic strategy against prion diseases

Location:
Institute of Neuropathology, University Medical Center Eppendorf

Grant Year:
2016

Rodrigo Morales, Ph.D.

Grant Title:
“Systematic Evaluation of the Zoonotic Potential of Different CWD Isolates”

Location:
Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, Department of Neurology, University of Texas-Houston Medical School

Grant Year:
2018

Jiyan Ma, PhD

Grant Title:
Determining the therapeutic potential of anti-PrP nanobody

Location: Professor, Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI

Grant Year: 2019

Simote Totauhelotu Foliaki, PhD

Grant Title:
Cerebral neuronal dysfunction associated with human prion diseases

Location:
National Institute of Allergy and Infectious Diseases, NIH

Grant Year: 2019

Candace Mathiason, PhD

Grant Title:
“Use of Blood-borne Prion Amplification Assays for the Detection of Human Prion Diseases and Biomarker Assessment”

Location:
Prion Research Center, Colorado State University

Grant Year:
2020

Robert C.C. Mercer, Ph.D.

Grant Title:
The identification of PrPSc interaction partners and the characterization of their role in prion infection and/or propagation

Location:
Instructor, Department of Biochemistry, Boston University School of Medicine

Grant Year: 2023

Qiuye Li, Ph.D.

Grant Title:
“High-resolution structure determination of MM1 and MM2 sCJD prions”

Location:
Department of Physiology and Biophysics, School of Medicine; Case Western Reserve University, Cleveland, OH

Grant Year: 2023

Victoria Lawson, PhD

Grant Title:
Risk of cancer from reduced expression of PrPC-implications for prion disease treatment”

Location:
Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Victoria, Australia

Grant Year: 2023

Jaime Noguez

Grant Title:
Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results

Location:
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH

Grant Year: 2022

Holger Wille, PhD

Grant Title:
Evaluating prion vaccines in transgenic mouse models of familial prion diseases

Location:
University of Alberta, Edmonton, Alberta, Canada

Grant Year: 2021

Simon Mead, PhD

Grant Title:
Genome-wide association study (GWAS) of age at clinical onset in inherited prion disease (genetic CJD)

Location:
University College London (UCL) Institute of Prion Diseases

Grant Year: 2021

Franc Llorens, PhD and Inga Zerr, MD

Grant Title:
Implementation of a blood-based biomarker test for sporadic Creutzfeldt-Jakob in clinical practice”

Location:
The Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Spain and German Center for Neurodegenerative Diseases

Grant Year:
2021

Stephanie Booth, PhD

Grant Title:
Detection and characterization of rare strains of sporadic Creutzfeldt-Jakob Disease using a suite of novel biological and biochemical tools

Location:
Public Health Agency of Canada and University of Manitoba.

Grant Year: 2021

Alberto Bizzi, MD

Grant Title:
Early diagnosis of CJD from in vivo MRI using the trajectories of prion lesion propagation

Location:
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy

Grant Year: 2021

Emiliano Biasini, PhD

Grant Title:
Pharmacological Degraders for the Cellular Prion Protein

Location:
University of Trento, Italy

Grant Year:
2021

Fei Wang, PhD

Grant Title:
Generating Recombinant Human Prions in Large Scale for Structural Studies

Location:
The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders; The University of Texas Health Science Center at Houston

Grant Year: 2020

Sonia Vallabh

Grant Title:
Assessing efficacy of zinc-finger repressors of prion protein as a therapeutic for prion disease

Location:
Broad Institute of MIT and Harvard

Grant Year: 2020

Qingzhong Kong, PhD

Grant Title:
The RAP approach for effective prevention and treatment of prion diseases

Location:
Case Western Reserve University

Grant Year:
2020

Natalia do Carmo Ferreira de Araujo

Grant Title:
Evaluation of new anti-prion drugs: from drug design to therapeutic efficacy against human prions in vitro, ex-vivo and in vivo

Location:
Rocky Mountain Laboratories, NIH/NIAID

Grant Year: 2020