
Alyssa Block, PhD
Grant Title: Refined transgenetic approaches to investigate selective adaptation of human prions during intracranial and peripheral transmissions
Location: Prion Research Center, Colorado State University
Grant Year: 2025
Contributed by: Sandra (Cookie) Stivison
Established in 2015

Grant Title: Refined transgenetic approaches to investigate selective adaptation of human prions during intracranial and peripheral transmissions
Location: Prion Research Center, Colorado State University
Grant Year: 2025
Grant Title:
Validation of a non-invasive diagnostic test for prion diseases using tear fluid
Location:
Dementia Research Unit, Dept. of Neurology in Göttingen, National Reference Center for TSE and German Center for Neuro-degenerative diseases, Germany
Grant Year: 2024

Grant Title:
Understanding the molecular mechanism of spontaneous prion emergence in knock-in mouse models
Location:
Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto
Grant Year: 2024

Grant Title:
Mechanisms of Selective Neuronal Vulnerability in Human Prion Disease
Location:
University of California, San Diego
Grant Year:
2015

Grant Title:
Combination therapies for human prion disease
Location:
Department of Medicine, University of Alberta
Grant Year:
2016

Grant Title:
Assessing Prions in Sporadic CJD Patients
Location:
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, Cleveland, Ohio
Grant Year:
2017

Grant Title:
Worms: A novel genetic model for therapeutic research in prion disease
Location:
Alzheimer’s and Prion diseases Lab at the Brain & Spine Institute (ICM) of the Salpêtrière Hospital, Sorbonne Université, Paris, France
Grant Year:
2017

Grant Title:
“Systematic Evaluation of the Zoonotic Potential of Different CWD Isolates”
Location:
Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, Department of Neurology, University of Texas-Houston Medical School
Grant Year:
2018

Grant Title:
“Investigation of Prion Inactivation by Reactive Oxygen Species in Vivo”
Location:
Rocky Mountain Laboratories, Montana
Grant Year:
2018

Grant Title:
Determining the therapeutic potential of anti-PrP nanobody
Location: Professor, Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI
Grant Year: 2019

Grant Title: Development of a quantitative, real-time Protein-Misfolding by Cyclic Amplification (PMCA) reaction
Location: Medical Research Council (MRC) Prion Unit at University College London
Grant Year: 2019

Grant Title:
Generation of Humanised STX6 Overexpression Mice to Study Prion Disease Genetic Risk and as a Model for Therapeutic Intervention
Location:
MRC Prion Unit at UCL, Institute of Prion Diseases, London
Grant Year: 2023

Grant Title:
Detection of residual prions from decontaminated medical and laboratory surfaces
Location:
School of Medicine, Creighton University, Omaha, NE
Grant Year: 2023

Grant Title:
Improving the sensitivity of CSF RT-QuIC in humans by examining cases with indeterminate results
Location:
National Prion Disease Pathology Surveillance Center, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH
Grant Year: 2022

Grant Title:
“Regional tropism of sporadic CJD subtypes in human brain organoids”
Location:
Laboratory of Neurological Infections and Immunity (LNII), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research, Rocky Mountain Laboratories, National Institutes of Health, Hamilton, MT
Grant Year: 2022

Grant Title:
The Contribution of Rare Variant and Copy-Number Variation to Risk of Sporadic CJD and Pleiotropy with Other Neurodegenerative Diseases
Location:
Washington University School of Medicine
Grant Year: 2020

Grant Title:
The RAP approach for effective prevention and treatment of prion diseases
Location:
Case Western Reserve University
Grant Year:
2020